This animation was inspired by an anti-drug poster, which showed two brain scans and the text “Have you changed your mind?”. Since the target audience was obviously not neuroscientists or brain surgeons, the only way to interpret it was based on the context, in which the connotation was presumably that one of the scans is a “damaged” drug-user’s brain, and the other is a healthy D.A.R.E. graduate.
Ironically, in a different context, the image becomes pro-drug. The word “psychedelic” is from the Greek roots psyche (mind) and delos (to manifest or become). Psychedelic means “mind-making”, or even, quite literally, “mind changing”. To those who have had positive, responsible, drug experiences, the poster might as well be channeling Jimi Hendrix: Are you experienced?